High-pressure in-line filter is a stand-alone version of the Trident column protection system, specifically designed for ease of use, low dead-volume, and flexibility. The filter has a replaceable, PEEK encapsulated 316 stainless steel frit with a surface area of 12 mm2. The standard frit with 2.0 μm porosity may be replaced with an optional 0.5 μm porosity frit. Use of this filter can greatly extend column life, thereby reducing costs and saving maintenance time. Tubing 1/16″ OD; connectors–CPI.